SC 13G


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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13G

Under the Securities Exchange Act of 1934
(Amendment No. )*

Inovio Biomedical Corp.

(Name of Issuer)

Common Stock, $0.001 par value

(Title of Class of Securities)

371916107

(CUSIP Number)

December 30, 2005

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

o Rule 13d-1(b)

þ Rule 13d-1(c)

o Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

TABLE OF CONTENTS


Item 1.
Item 2.
Item 3.
Item 4. Ownership.
Item 5. Ownership of Five Percent or Less of a Class
Item 6. Ownership of More than Five Percent on Behalf of Another Person.
Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person
Item 8. Identification and Classification of Members of the Group
Item 9. Notice of Dissolution of Group
Item 10. Certification
SIGNATURE


CUSIP No.		371916107		Page		2		of		5


1	NAMES OF REPORTING PERSONS: Merck & Co., Inc.

	I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY):


2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):
	(a) o
	(b) o

3	SEC USE ONLY:



4	CITIZENSHIP OR PLACE OF ORGANIZATION:

	New Jersey

		5	SOLE VOTING POWER:

NUMBER OF			1,687,500

SHARES		6	SHARED VOTING POWER:
BENEFICIALLY
OWNED BY

EACH		7	SOLE DISPOSITIVE POWER:
REPORTING
PERSON			1,687,500

WITH:		8	SHARED DISPOSITIVE POWER:



9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

	1,687,500

10	CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):

	o

11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):

	5.64%

12	TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):

	CO

Item 1.

	(a)		Name of Issuer:

			Inovio Biomedical Corp.

	(b)		Address of Issuer’s Principal Executive Offices:

			11494 Sorrento Valley Road San Diego, California 92121-1318

Item 2.

	(a)		Name of Person Filing:

			Merck & Co., Inc.

	(b)		Address of Principal Business Office or, if none, Residence:

			One Merck Drive, Whitehouse Station, NJ 08889

	(c)		Citizenship:

			NJ

	(d)		Title of Class of Securities:

			Common Stock, par value $0.001

	(e)		CUSIP Number:

			371916107

Item 3.

Not applicable as this Schedule is filed pursuant to Rule 13d-1(c).

Item 4. Ownership.

Provide the following information regarding the aggregate number and percentage
of the class of securities of the issuer identified in Item 1.

	(a)		Amount beneficially owned: 1,687,500.

	(b)		Percent of class: 5.64%.

	(c)		Number of shares as to which the person has:

	(i)		Sole power to vote or to direct the vote 1,687,500.

	(ii)		Shared power to vote or to direct the vote .

	(iii)		Sole power to dispose or to direct the disposition of 1,687,500.

	(iv)		Shared power to dispose or to direct the disposition of .

Item 5. Ownership of Five Percent or Less of a Class

Not Applicable.

Item 6. Ownership of More than Five Percent on Behalf of Another Person.

Not Applicable.


Item 7.		Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person

Not Applicable.

Item 8. Identification and Classification of Members of the Group

Not Applicable.

Item 9. Notice of Dissolution of Group

Not Applicable.

Item 10. Certification

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.


		January 9, 2006

		Date

		/s/ Celia A. Colbert

		Signature

		Celia A. Colbert Vice President, Secretary and Assistant General Counsel

		Name/Title

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